Transcriptomics

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CRISPR-Cas9 combinatorial KO of epigenetic regulators in human ovarian cancer cells


ABSTRACT: We sequenced polyA mRNA from OVCAR8-ADR-Cas9 cells in which one or two of 3 epigenetic regulators (BRD4, KDM4C, KDM6B) had been knocked out to examine how global gene expression was affected and evaluate potential synergistic effects at a molecular level.

ORGANISM(S): Homo sapiens

PROVIDER: GSE71074 | GEO | 2015/12/17

SECONDARY ACCESSION(S): PRJNA290313

REPOSITORIES: GEO

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