Transcriptomics

Dataset Information

0

Effects of bromodomain inhibitors on CD4 T+ cells under Th17-promoting conditions


ABSTRACT: The human dataset includes the gene expression profile of CD4+ T cells isolated from blood of healthy controls and plated on TCP in RPMI-1640 containing 10% FCS, Penicillin-Streptomycin (50,000 units-50 mg) and L-glutamine (2 mM). Cells were stimulated for 4 days with 20 ng/ml of IL-1beta, 100 IU/ml of IL-2, 20 ng/ml of IL-6, 20 ng/ml IL-23 plus anti-CD2/3/28 beads at a ratio of 1 bead per 10 cells. RNA samples were isolated using the RNeasy Mini Kit (Qiagen) with on-column DNA digestion. The transcriptional profile was evaluated in three different donors using the HT12v4.1 BeadChip arrays from Illumina.

ORGANISM(S): Homo sapiens

PROVIDER: GSE71231 | GEO | 2015/07/23

SECONDARY ACCESSION(S): PRJNA290644

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2015-07-23 | E-GEOD-71231 | biostudies-arrayexpress
2011-09-15 | E-GEOD-32164 | biostudies-arrayexpress
2014-12-22 | E-MEXP-3959 | biostudies-arrayexpress
2024-10-10 | PXD056475 | Pride
2015-06-01 | GSE64177 | GEO
2012-05-19 | GSE35304 | GEO
2018-11-30 | MSV000083175 | MassIVE
2017-02-28 | GSE95405 | GEO
2019-03-29 | PXD012052 | Pride
2013-07-26 | GSE49240 | GEO