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Dynamics of H3K4me2 during cardiac lineage reprogramming

ABSTRACT: During reprogramming of fibroblasts into cardiomyocyte-like cells by overexpression of transcription factors, GATA4, Hand2, Mef2C and Tbx5 (GHMT), H3K4Me2, an active histone code, shifts from fibroblast-exclusive peaks to cardiomyocyte-exclusive peaks. Important cardiac genes are gradually marked by this active histone marker.

ORGANISM(S): Mus musculus

PROVIDER: GSE71392 | GEO | 2015/07/28

SECONDARY ACCESSION(S): PRJNA291082

REPOSITORIES: GEO

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Dynamics of H3K4me2 during cardiac lineage reprogramming

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