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A transcription factor pulse can prime chromatin for heritable transcriptional memory [ChIPseq]

ABSTRACT: To investigate the epigenetic control of long-term transcriptionnal memory (LTTM) we used a trans-differentiation system where Bcell are reprogramed into macrophages upon induction of the transcription factor Cebpa. We performed ChIPseq in untreated Bcells, after 12h of Cebpa induction and after 6days of “wash” of Cebpa, to see if any proteins/histone marks are retained.

ORGANISM(S): Mus musculus

PROVIDER: GSE72486 | GEO | 2016/12/21

SECONDARY ACCESSION(S): PRJNA294146

REPOSITORIES: GEO

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