Assessment of ability of hTSLP to maintain primary CRLF2 B-ALL cells in a xenograft model in a state more similar to the parent leukemia
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ABSTRACT: Xenograft models represent an excellent method for expanding primary leukemias, but their ability to preserve the gene expression profile of the parent leukemia may also depend on providing microenvironmental factors that are not cross-reactive between human and mouse. Here we focused on leukemias with a CRLF2 mutation, and the ability of human TSLP to stimulate these cells.
ORGANISM(S): Homo sapiens
PROVIDER: GSE74339 | GEO | 2015/12/31
SECONDARY ACCESSION(S): PRJNA299771
REPOSITORIES: GEO
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