Transcriptomics

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Genome-wide analysis of gefitinib short-term resistance gene expression in the NSCLC cell line PC9 in co-culture


ABSTRACT: Analysis of gefitinib short-term resistance at gene expression level. The hyposthesis tested in the present study was that short-term resistance towards gefitinib in NSCLC cells influences pathways that associates with resistance towards EGFR-TKI treatment. Results provide important information of the response of EGFR mutant NSCLC cells to gefitinib and also to resistance towards gefitinib resistance, up-or down-regulated specific resistance pathways and cellular functions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE75308 | GEO | 2016/07/01

SECONDARY ACCESSION(S): PRJNA303163

REPOSITORIES: GEO

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