A PhoP point mutation discriminates between the virulent H37Rv and avirulent H37Ra strains of Mycobacterium tuberculosis
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ABSTRACT: To uncover mutations underlying the attentuation of H37Ra, we embarked on sequencing its genome using a novel massive parallel pyrosequencing technology. Comparison with the virulent H37Rv parental strain revealed only few polymorphisms, one of which was located in the DNA binding domain of the transcriptional regulator PhoP. Keywords: Expresion profiling
ORGANISM(S): Mycobacterium tuberculosis Mycobacterium tuberculosis H37Ra Mycobacterium tuberculosis H37Rv
PROVIDER: GSE7539 | GEO | 2007/07/05
SECONDARY ACCESSION(S): PRJNA99369
REPOSITORIES: GEO
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