Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers
Ontology highlight
ABSTRACT: We examined the transcriptional chagnes modulated by ECBI-11 by perfroming global transcriptome analysis. ZR75 cells were treated with either control or ECBI-11 in the presence of E2 for 48 h and the isolated RNA was utilized for RNA-seq analysis. Our results demonstrated that ECBI modulated several genes that are involved in cell cycle, breast cancer signaling, estrogen signaling and apoptosis.
ORGANISM(S): Homo sapiens
PROVIDER: GSE75664 | GEO | 2017/08/18
SECONDARY ACCESSION(S): PRJNA305002
REPOSITORIES: GEO
ACCESS DATA