Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Analysis of mature miRNA levels in the context of CHO cell proliferation

ABSTRACT: Mature microRNA transcripts were analyzed in 9 CHO cell lines growing at different proliferation rates. The goal was to identify microRNAs that correlate positively or negatively with CHO proliferation rates.

ORGANISM(S): Mus musculus Rattus norvegicus Homo sapiens Cricetulus griseus

PROVIDER: GSE75830 | GEO | 2015/12/10

SECONDARY ACCESSION(S): PRJNA305504

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Analysis of mature miRNA levels in the context of CHO cell proliferation

2014-01-07 | GSE52994 | GEO

Analysis of mature miRNA levels in the context of CHO cell proliferation

Project description:mature microRNA transcripts were analyzed in 5 CHO cell lines growing at different proliferation rates. The goal was to identify microRNAs that correlate positively or negatively with CHO proliferation rates. A common reference design was chosen, where all samples were hybridized against a pool of all RNA samples.

2014-01-07 | E-GEOD-52994 | biostudies-arrayexpress

Analysis of mature miRNA levels in the context of CHO cell proliferation

Project description:Mature microRNA transcripts were analyzed in 9 CHO cell lines growing at different proliferation rates. The goal was to identify microRNAs that correlate positively or negatively with CHO proliferation rates. A common reference design was chosen, where all samples were hybridized against a pool of all RNA samples.

2015-12-10 | E-GEOD-75830 | biostudies-arrayexpress

Expression data from CHO-K1 cells in putrescine-deprived conditions

Project description:CHO cells grown in serum-free medium have an absolute requirement for putrescine supplementation due to their deficiency in activity of the enzyme arginase. Consequently, principally in this system, polyamines play a central but poorly-understood role in cell proliferation Cell growth arrest, mainly in the S- and G2/M phases was observed. We used differential gene expression data to investigate the impact of polyamine deprivation on the transcriptome of CHO cells

2019-12-12 | GSE140223 | GEO

Hyperosmolality in CHO Culture: Effects on Proteome

Project description:Chinese hamster ovary cells (CHO) were exposed to highly concentrated feed solution during a fed-batch cultivation which causes an unphysiological osmolality increase (>300 mOsm/kg) affecting cell physiology, morphology and proteome. To get a deeper insight into underlying molecular mechanisms involved in cellular hyperosmolality response, we performed a comparative quantitative label-free proteome study of hyperosmolality-exposed vs. control CHO cells by nanoLC-ESI-MS measurement approach (orbitrap-MS). Our observations correlate well with the data from recent CHO-based fluxome and transcriptome studies and expose hitherto unknown targets involved in response to hyperosmotic pressure in mammalian cells.

2022-05-20 | PXD027443 | Pride

CHO-S transcriptome in batch culture

Project description:Transcriptomic data from CHO-S cells were gathered from multiple time points during batch culture to provide information about gene presence/absence for generation of a CHO-S cell line specific model using the GIMME algorithm.

2016-11-23 | GSE77800 | GEO

Cricetulus griseus strain:CHO

Project description:CHO-DG44

| PRJDB5831 | ENA

CHO cells: Serum free adapted cells (Control) vs. Serum adapted cells

Project description:Transcriptional profiling of CHO-K1 cells comparing to in-house serum-free and suspension adapted CHO-K1 cells in the exponential phase. Goal was to determine the effects of serum on CHO-K1 cells.

2016-12-24 | GSE92885 | GEO

Cricetulus griseus strain:CHO-K1

Project description:CHO cells

| PRJDB4351 | ENA

Identification of microRNAs specific for high producer CHO cell lines

Project description:Mature microRNA levels were analyzed in 4 producing CHO cell lines expressing 2 structurally different recombinant proteins at low and high level as well as in 1 non-producing CHO cell line. The goal was to identify microRNAs that are involved in heterologous protein formation and secretion. 5 recombinant CHO cell lines. 3 biological replicates each. All samples were hybridized against a common reference (pool of all total RNA samples).

2014-08-04 | E-GEOD-57023 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data