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Expression data from glioblastoma stem cells

ABSTRACT: TLX (NR2E1), as an orphan nuclear receptor, plays a critical role in growth, self-renewal, and tumorigenesis of glioblastoma stem cells. We used microarrays to investigate the global gene expression regulated by TLX and identified downstream targets of TLX in glioblastoma stem cells. We further investigated the global gene expression regulated by TET3, a downstream target of TLX, to identified downstream targets of TLX-TET3 axis in glioblastoma stem cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE75945 | GEO | 2016/02/01

SECONDARY ACCESSION(S): PRJNA305760

REPOSITORIES: GEO

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Transcription profiling of mouse Tlx-positive neural stem cells isolated from 2-month-old male to investigate Tlx (nr2e1)-dependent gene expression in adult neural stem cells

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