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Circulating microRNA screening of high-risk individuals enrolled in COSMOS lung cancer screening trial.

ABSTRACT: Lung cancer is the leading cause of cancer death worldwide. Low-dose computed tomography screening (LDCT) was recently shown to anticipate the time of diagnosis, thus reducing lung cancer mortality. We identifed a serum microRNA signature (the miR-Test) that could identify the optimal target population for LDCT screening. Here, we performed a large-scale validation study of the miR-Test in high-risk individuals enrolled in the Continuous Observation of Smoking Subjects (COSMOS) lung cancer screening program.

ORGANISM(S): Homo sapiens

PROVIDER: GSE76462 | GEO | 2016/02/29

SECONDARY ACCESSION(S): PRJNA307356

REPOSITORIES: GEO

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Circulating microRNA screening of high-risk individuals enrolled in COSMOS lung cancer screening trial.

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