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Methylomes and Transcriptomes of Human Pluripotent-to-Cardiomyocyte Differentiation [RNA-seq]

ABSTRACT: In this report, Tompkins et al describe the derivation, differentiation stage-specific purification, and genome-wide analysis of cardiomyocytes derived from hESCs. Key features of the molecular programs that define human cardiac muscle cell differentiation were described and researchers observed that cells may harbor epigenetic DNA methylation “memories” that reflect the gene activation history of important developmental genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE76523 | GEO | 2016/01/30

SECONDARY ACCESSION(S): PRJNA307622

REPOSITORIES: GEO

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