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Mapping transcriptionally engaged RNA polymerase II in C2C12 myoblasts

ABSTRACT: A large portion of the mammalian genome is associated with the nuclear lamina (NL). Here we have documented genome-wide transcriptional activities by measuring the densities, locations and orientations of transcriptionally-engaged RNA polymerase II in mouse C2C12 myoblasts using global run-on sequencing. Interestingly, a significant fraction (~20%) of NL-associated genes were detected to be transcriptionally active.

ORGANISM(S): Mus musculus

PROVIDER: GSE76624 | GEO | 2017/06/13

SECONDARY ACCESSION(S): PRJNA308190

REPOSITORIES: GEO

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