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Differentially expressed genes in c2c12 myoblasts

ABSTRACT: Proteosome inhibitors such as bortezomib (BTZ) have been used to treat muscle wasting in animal models. However, direct effect of BTZ on skeletal muscle cells has not been reported. In the present study, our data showed that C2C12 cells exhibited a dose-dependent decrease in cell viability in response to increasing concentrations of BTZ. We used microarrays to detail the differentially expressed genes in c2c12 myoblasts with different culture conditions.

ORGANISM(S): Mus musculus

PROVIDER: GSE92671 | GEO | 2016/12/23

SECONDARY ACCESSION(S): PRJNA358619

REPOSITORIES: GEO

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