Genomics

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Genome-wide screening of HNF1b binding sites identifies transcriptional regulation of the Kir4.1/Kir5.1 potassium channel


ABSTRACT: chIP-seq was used to provide a genome-wide screening of transcription factor HNF1B binding sites to further elucidate its effect on cyst formation, diabetes and electrolyte handling in patients. A highly specific dataset for Hnf1b binding was constructed for an immortalized murine DCT cell line (mpkDCT4a).

ORGANISM(S): Mus musculus

PROVIDER: GSE77397 | GEO | 2017/08/01

SECONDARY ACCESSION(S): PRJNA310219

REPOSITORIES: GEO

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