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Primary human blood-derived macrophages (BDMs): control vs. infected

ABSTRACT: Transcriptional profiling of primary human blood-derived macrophages (BDMs) comparing control untreated BDMs with BDMs exposed with Streptococcus pneumoniae strain D39 (MOI 0.1 and 0.5) for 16 hours)

ORGANISM(S): Homo sapiens

PROVIDER: GSE77561 | GEO | 2016/06/15

SECONDARY ACCESSION(S): PRJNA310851

REPOSITORIES: GEO

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Primary human blood-derived macrophages (BDMs): control vs. infected

Project description:Transcriptional profiling of primary human blood-derived macrophages (BDMs) comparing control untreated BDMs with BDMs exposed with Streptococcus pneumoniae strain D39 (MOI 0.1 and 0.5) for 16 hours) Two-condition experiment, control BDMs vs. infected BDMs. Biological replicates: 3 control replicates, 3 infected replicates MOI 0.1, 2 infected replicates MOI 0.5).

2016-06-15 | E-GEOD-77561 | biostudies-arrayexpress

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N-acetylgalactosamine Mediated Regulation of the aga Operon by AgaR in Streptococcus pneumoniae

Project description:Three Microarray comparisons have been preformed in this study. 1- Transcriptome comparison of the Streptococcus pneumoniae D39 wild type grown in M17 medium + 0.5 % (w/v) NAGa (NAGaM17) to M17 medium + 0.5 % (w/v) glucose (GM17) (GSM2372597 and GSM2372598). 2- Transcriptome comparison of the Streptococcus pneumoniae D39 ΔagaR to D39 wild type grown in M17 medium + 0.5 % (w/v) glucose (GM17) (GSM2372599 and GSM2372600). 3- Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild type grown in M17 medium + 0.5 % (w/v) NAGa (NAGaM17) (GSM2290636 and GSM2290637).

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Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔbguR to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

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Impact of rokA delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of Glucose

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔrokA to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

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Impact of ccpA delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of Glucose

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild-type grown in M17 medium + 0.5% glucose (GM17).

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Impact of nanR delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of sialic acid

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Impact of ccpA delation on the transcriptome of Streptococcus pneumoniae D39 in the presece of N-acetylglucosamine (NAG)

Project description:Transcriptome comparision of the Streptococcus pneumoniae D39 ccpA mutant to D39 wild-type grown in CDM + 0.5 % N-acetylglucosamine (NAG)

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Impact of ccpA delation on the transcriptome of Streptococcus pneumoniae D39 in the presence of sialic acid

Project description:Transcriptome comparison of the Streptococcus pneumoniae D39 ΔccpA to D39 wild-type grown in M17 medium + 0.5% sialic acid (SM17).

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