Transcriptomics

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Vancomycin nephrotoxicity assessed by DNA microarray


ABSTRACT: The glycopeptide antibiotic vancomycin (VCM) represents one of the last lines of defense against methicillin-resistant Staphylococcus aureus infections. However, vancomycin is nephrotoxic, but the mechanism of toxicity is still unclear. The goal of this study was twofold: (1) gain insights into the molecular mechanisms of vancomycin nephrotoxicity at the genomic level and (2) evaluate potential biomarkers (gene expression profiles) of vancomycin-induced kidney injury Keywords: Dose response

ORGANISM(S): Mus musculus

PROVIDER: GSE7793 | GEO | 2008/10/23

SECONDARY ACCESSION(S): PRJNA99821

REPOSITORIES: GEO

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