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RNA-Seq of subcutaneous inguinal white fat of Hlx transgenic mice and littermate controls.

ABSTRACT: RNA-Seq of subcutaneous inguinal white fat of Hlx transgenic mice and littermate controls.

ORGANISM(S): Mus musculus

PROVIDER: GSE78143 | GEO | 2017/08/11

SECONDARY ACCESSION(S): PRJNA312769

REPOSITORIES: GEO

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Interaction between PPARγ and mTORC1 in the regulation of inguinal white adipose tissue transcriptome

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Genes upregulated by HLX

Project description:HLX was found as a VEGF-A induced gene in HUVEC (B.Schweighofer, submitted). In order to detect genes regulated by HLX HUVEC were infected by recombinant adenovirus expressing HLX for 4, 8, 16 and 32h. RNA was isolated and subjected to microarray analysis using Affymetrix microarray. HUVEC were infected with a MOI of 40 with either HLX expressing or empty adenovirus for 4, 8, 16 or 32 hours. HUVEC without an adenovirus infection were used as control.Total RNA was isolated with Trizol according to the instructions of the manufacturer. Gene expression was analysed with Affymetrix GeneChip Human Genome U133 Plus 2.0 Arrays according to the Affymetrix protocol.

2011-02-15 | E-GEOD-13054 | biostudies-arrayexpress

Mus musculus

Project description:RNA-Seq of subcutaneous inguinal white fat of Hlx transgenic mice and littermate controls.

| PRJNA312769 | ENA

Genes upregulated by HLX

2011-02-15 | GSE13054 | GEO

RNA-sequence analysis of immortalized, differentiated preadipocytes derived from inguinal subcutaneous white adipose tissue.

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Project description:Adult mouse were kept at room temperature, RNAseq was performed for interscapular brown, subscapular white and inguinal white adipose tissue

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