Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Profile of microRNAs in human umblical vein endothelial cells (HUVECs)

ABSTRACT: Polychlorinated biphenyl exposure alters the expression profile of microRNAs in HUVECs

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE79005 | GEO | 2016/08/31

SECONDARY ACCESSION(S): PRJNA314678

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

TNF-alpha-stimulated human umblical vein endothelial cells (HUVECs)

Project description:TNF-alpha-stimulated human umblical vein endothelial cells (HUVECs)

| PRJNA501790 | ENA

MicroRNA signature of young and replicative senescent human umbilical vein endothelial cells (HUVECs)

Project description:MicroRNAs regulate various cellular processes. While several genes associated with replicative senescence have been described in endothelial cells, miRNAs that regulate these genes remain largely unknown. The present study was designed to identify miRNAs associated with replicative senescence and their target genes in HUVECs. We have employed Agilent Human MicroRNAs microarray platform to evaluate the expressions of 866 human miRNAs and 89 human viral miRNAs, based on Sanger miRNA database release 12.0 miRNA expression profiles were established for young and replicative senescent HUVECs

2013-04-05 | E-GEOD-37092 | biostudies-arrayexpress

Gene signature of young and replicative senescent human umbilical vein endothelial cells (HUVECs)

Project description:MicroRNAs regulate various cellular processes. While several genes associated with replicative senescence have been described in endothelial cells, miRNAs that regulate these genes remain largely unknown. The present study was designed to identify miRNAs associated with replicative senescence and their target genes in HUVECs. Gene profiling was established using the same RNA input as that used for miRNA profiing. We have employed Agilent Whole Human Genome microarray platform to evaluate the expressions of 19,596 human genes . Gene expression profiles were established for young and replicative senescent HUVECs

2013-04-05 | E-GEOD-37091 | biostudies-arrayexpress

The genome expression profile of human umbilical vein endothelial cells (HUVECs) overexpressing miR-146a

Project description:Endothelial cells are critical for angiogenesis, and microRNAs plays important roles in this process. We investigated the regulatory role of microRNAs in endothelial cells of hepatocellular carcinoma (HCC) by examining the microRNA expression profile of human umbilical vein endothelial cells (HUVECs) in the absence or presence of human HCC cells, and identified miR-146a as the most highly up-regulated microRNA. Furthermore, we revealed that miR-146a promoted the expression of platelet-derived growth factor receptor (PDGFRA) in HUVECs, and this process was mediated by BRCA1. Overexpression of PDGFRA in the ECs of HCC tissues was associated with microvascular invasion, and predicted a poorer prognosis. These results suggest that MiR-146a plays a key role in regulating the angiogenic activity of ECs in HCC through miR-146a-BRCA1-PDGFRA pathway. MiR-146a may emerge as a potential anti-angiogenic target on ECs for HCC therapy. We have employed whole genome OneArray to examine the genome expression changes of HUVECs overexpressing miR-146a.

2013-04-13 | E-GEOD-46022 | biostudies-arrayexpress

TNF-alpha-stimulated human umblical vein endothelial cells (HUVECs)

Project description:This SuperSeries is composed of the SubSeries listed below.

2019-04-11 | GSE121522 | GEO

MicroRNA signature of young and replicative senescent human umbilical vein endothelial cells (HUVECs)

2013-04-05 | GSE37092 | GEO

The genome expression profile of human umbilical vein endothelial cells (HUVECs) overexpressing miR-146a

2013-04-13 | GSE46022 | GEO

Gene signature of young and replicative senescent human umbilical vein endothelial cells (HUVECs)

Project description:MicroRNAs regulate various cellular processes. While several genes associated with replicative senescence have been described in endothelial cells, miRNAs that regulate these genes remain largely unknown. The present study was designed to identify miRNAs associated with replicative senescence and their target genes in HUVECs. Gene profiling was established using the same RNA input as that used for miRNA profiing. We have employed Agilent Whole Human Genome microarray platform to evaluate the expressions of 19,596 human genes .

2013-04-05 | GSE37091 | GEO

Hi-C analysis in TNF-alpha-stimulated human umblical vein endothelial cells (HUVECs)

Project description:Hi-C analysis in TNF-alpha-stimulated human umblical vein endothelial cells (HUVECs)

| PRJNA497537 | ENA

miRNA expression data through TNF-alpha-signaling in human umblical vein endothelial cells (HUVECs)

Project description:miRNA expression data through TNF-alpha-signaling in human umblical vein endothelial cells (HUVECs)

| PRJNA521957 | ENA