Transcriptomics

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Genome-wide expression microarray analysis of SOX2-deficient TCam-2 cells in vivo


ABSTRACT: Illumina expression microarray analysis of seminoma-like TCam-2 cells depleted for SOX2 by CRISPR/Cas9. Cells were xenografted in nude mice. 2120EP embryonal carcinoma and parental TCam-2 cells were xenograted as controls. Tumors were recovered after 1 (1w) and 6 weeks (clone 1 - 5) of in vivo growth. Additionally, in vitro cultivated TCam-2 were analyzed as control. The data set is part of the study 'SOX2 is essential for in vivo reprogramming of seminoma-like TCam-2 cells to an embryonal carcinoma-like fate' (Nettersheim et al., 2016, Oncotarget).

ORGANISM(S): Homo sapiens

PROVIDER: GSE79065 | GEO | 2016/05/22

SECONDARY ACCESSION(S): PRJNA314852

REPOSITORIES: GEO

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