Transcriptomics

Dataset Information

0

A molecular portrait of epithelial-mesenchymal plasticity in prostate cancer associated with clinical outcome.


ABSTRACT: The propensity of cancer cells to transition between epithelial and mesenchymal phenotypic states is considered to be critical in metastatic processes, cancer progression, and treatment resistance. To investigate a transient epithelial-mesenchymal transition (EMT) in prostate adenocarcinoma, LNCaP cells with inducible and reversible expression of SNAI1 or SNAI2 were generated. Cells were treated with doxycycline to induce a SNAI1- or SNAI2-mediated EMT for 5 days and then subsequently removed for 3, 5, and 20 days to allow for MET. LNCaP-iGFP cells were also generated for control purposes and were subjected to the same treatment regime.

ORGANISM(S): Homo sapiens

PROVIDER: GSE80042 | GEO | 2018/09/11

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2021-10-01 | GSE161551 | GEO
2019-12-17 | GSE113288 | GEO
2019-12-17 | GSE113283 | GEO
2019-12-17 | GSE113279 | GEO
2013-09-30 | GSE40690 | GEO
2013-09-30 | E-GEOD-40690 | biostudies-arrayexpress
2017-11-07 | MTBLS387 | MetaboLights
2022-07-08 | PXD033530 | Pride
2011-10-12 | E-GEOD-27260 | biostudies-arrayexpress
2020-06-30 | MODEL2004040001 | BioModels