Transcriptomics

Dataset Information

0

AML1-ETO transduced human cord blood cells, CD34 selected, compared to normal cord blood cells, CD34 selected


ABSTRACT: AML1-ETO expression in normal human umbilical cord blood CD34+ cells leads to long-term proliferation of an early self-renewing primitive progenitor cell with multilineage potential and stem cell ability, but these cells do not induce leukemia in immunodeficient mice. This comparative microarray study was initiated to determine the differences in the transcriptome of AML-ETO-expressing CD34+ cells after extended culture in vitro, using normal cord blood cells expanded for 6-8 weeks in vitro and subsequently purified for the CD34+ population as the control comparison. Keywords: Disease state analysis; comparison of changes in transcriptome due to long-term AML1-ETO expression in normal human hematopoietic CD34+ progenitor cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE8023 | GEO | 2007/12/20

SECONDARY ACCESSION(S): PRJNA100827

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2008-06-15 | E-GEOD-8023 | biostudies-arrayexpress
2011-07-19 | GSE28317 | GEO
2011-07-18 | E-GEOD-28317 | biostudies-arrayexpress
2007-08-30 | E-GEOD-2049 | biostudies-arrayexpress
2019-01-01 | E-MTAB-3466 | biostudies-arrayexpress
| PRJNA754146 | ENA
2005-03-01 | GSE2049 | GEO
2008-05-01 | GSE7011 | GEO
2008-06-15 | E-GEOD-7011 | biostudies-arrayexpress
2017-06-23 | GSE100354 | GEO