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Genome-wide analysis of differential gene expression after Foxd3 knockdown in colorectal CDCP1+CSCs

ABSTRACT: Analysis of Foxd3-regulation of self-renewal and quiescence in CDCP1+CSCs at gene expression level. The hypothesis tested in the present study was that the Foxd3 global developmental regulator serves a critical role to support the self-renewal of CDCP1+CSCs as one of few known factors involved in maintaining their quiescence. Results provide important information of the response of colorectal CDCP1+CSCs to depletion of Foxd3, such as genes involved in regulation of cell cycle, cell proliferation, and stem-like properties.

ORGANISM(S): Mus musculus

PROVIDER: GSE80505 | GEO | 2016/04/22

SECONDARY ACCESSION(S): PRJNA319149

REPOSITORIES: GEO

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