Klf5 regulates muscle differentiation via directly targeted muscle-specific genes in cooperation with MyoD in mice
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ABSTRACT: Deletion of Klf5 in satellite cells impaired muscle regeneration due to a failure of differentiation. Mechanistically, Klf5 controls transcription of muscle genes by interacting with MyoD and Mef2. These findings provide a potential intervention into the process of muscle regeneration through modulation of Klf5.
ORGANISM(S): Mus musculus
PROVIDER: GSE80812 | GEO | 2016/10/14
SECONDARY ACCESSION(S): PRJNA320053
REPOSITORIES: GEO
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