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Transcriptomic analysis reveals the early signaling events of narciclasine in Arabidopsis root apex

ABSTRACT: we report the application of high throughput sequencing technology for digital gene expression profiling of the gene expression pattern in Arabidopsis root tips treated with 0.5 µM narciclasine at 2 and 12 hr.Compared with controls, 236 genes were upregulated and 54 genes were downregulated with 2 hrs of narciclasine treatment, while 968 genes were upregulated and 835 genes were down-regulated with 12 hrs of treatment. The Gene Ontology analysis revealed that the differentially expressed genes were highly enriched during oxidative stress, including those involved in the 'regulation of transcription', 'response to oxidative stress', 'plant-pathogen interaction', 'ribonucleotide binding', 'plant cell wall organization', and 'ribosome biogenesis'. Moreover, Kyoto Encyclopedia of Genes and Genomes pathway enrichment statistics suggested that carbohydrate metabolism, amino acid metabolism, amino sugar and nucleotide sugar metabolism, and biosynthesis of phenylpropanoid and secondary metabolites were significantly inhibited by 12 hrs of narciclasine exposure.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE80815 | GEO | 2019/04/19

REPOSITORIES: GEO

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