Proteomics

Dataset Information

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Proteome and sugar catabolization capacity of Lactococcus cremoris grown on various sugars

ABSTRACT: The lactic acid bacterium Lactococcus cremoris is suggested to repress genes involved in sugar metabolism in a hierarchical way, correlating with the growth rate. For cultures grown on glucose, lactose, galactose and maltose, we unraveled the sugar catabolizing hierarchy by combining the proteome composition and the capacity to catabolize a set of 12 sugars.

INSTRUMENT(S): LTQ Orbitrap XL

ORGANISM(S): Lactococcus Lactis Subsp. Cremoris Mg1363

SUBMITTER: Sjef Boeren  

LAB HEAD: Sjef Boeren

PROVIDER: PXD037169 | Pride | 2024-01-26

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
BvO307_Gal_5mM_1.raw Raw
BvO308_Gal_5mM_2.raw Raw
BvO309_Gal_5mM_3.raw Raw
BvO310_Mal_12p5mM_1.raw Raw
BvO311_Mal_12p5mM_2.raw Raw
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Publications

The hierarchy of sugar catabolization in <i>Lactococcus cremoris</i>.

Douwenga Sieze S   van Olst Berdien B   Boeren Sjef S   Luo Yanzhang Y   Lai Xin X   Teusink Bas B   Vervoort Jacques J   Kleerebezem Michiel M   Bachmann Herwig H  

Microbiology spectrum 20231027 6

<h4>Importance</h4>The availability of nutrients to microorganisms varies considerably between different environments, and changes can occur rapidly. As a general rule, a fast growth rate-typically growth on glucose-is associated with the repression of other carbohydrate utilization genes, but it is not clear to what extent catabolite repression is exerted by other sugars. We investigated the hierarchy of sugar utilization after substrate transitions in <i>Lactococcus cremoris</i>. For this, we  ...[more]

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