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APOL1 variant expression in mouse podocytes cause kidney disease

ABSTRACT: Next-generation sequencing (NGS) has become an important tool in molecular charactarization of animal models. APOL1 variants are associated with end stage renal disease in African Americans. We developed a mouse model with podocyte specific over expression of APOL1. Differential molecular signatures were identified between the groups by RNA-Sequencing on kidney.

ORGANISM(S): Mus musculus

PROVIDER: GSE81492 | GEO | 2017/02/15

SECONDARY ACCESSION(S): PRJNA321754

REPOSITORIES: GEO

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APOL1 renal-risk variants induce mitochondrial dysfunction (Affymetrix 2)

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