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Determination of Lsd1 function in brown adipose tissue by global transcriptome analysis [RNA-seq]

ABSTRACT: To investigate the role of Lsd1 in BAT, we crossed mice harboring conditional Lsd1 alleles (Zhu et al., 2014) with the Ucp1-Cre deleter strain (Turpin et al., 2014), which results in Cre-mediated loss of Lsd1 selectively in brown adipocytes. Transciptome analysis of BAT obtained from control and knock-out mice revealed 3322 genes differentially expressed between Lsd1 knock-out and control mice at 10 weeks of age (p-value<10-2).

ORGANISM(S): Mus musculus

PROVIDER: GSE81555 | GEO | 2016/10/27

SECONDARY ACCESSION(S): PRJNA321981

REPOSITORIES: GEO

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Determination of Lsd1 function in brown adipose tissue by global transcriptome analysis [RNA-seq]

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