Effect of SF3B1 suppression in cancer cells with different SF3B1 copy-number levels
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ABSTRACT: Breast cancer cell lines containing stable dox inducible shRNAs targeting SF3B1 were profiled by RNA sequencing. We determined the effect of gene expression and splicing changes before and after knocking down SF3B1 in cell lines with normal copy number (SF3B1neutral) or partial copy loss (SF3B1loss) cell lines
ORGANISM(S): Homo sapiens
PROVIDER: GSE81978 | GEO | 2017/02/07
SECONDARY ACCESSION(S): PRJNA323711
REPOSITORIES: GEO
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