Transcriptomics

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Single cell RNA-seq of human pancreatic endocrine cells from Juvenile, adult control and type 2 diabetic donors.


ABSTRACT: We successfully sequenced and annotated more than 400 cells from child, adult control, type 1 diabetes and type 2 diabetes donors. We detect donor-type specific transcript variation. We also report that cells from child donors have less defined gene signature. Cells from type 2 diabetes donors resemble juvenile cells in gene expression.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83139 | GEO | 2016/07/05

SECONDARY ACCESSION(S): PRJNA325005

REPOSITORIES: GEO

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