Single cell RNA-seq of human pancreatic endocrine cells from Juvenile, adult control and type 2 diabetic donors.
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ABSTRACT: We successfully sequenced and annotated more than 400 cells from child, adult control, type 1 diabetes and type 2 diabetes donors. We detect donor-type specific transcript variation. We also report that cells from child donors have less defined gene signature. Cells from type 2 diabetes donors resemble juvenile cells in gene expression.
ORGANISM(S): Homo sapiens
PROVIDER: GSE83139 | GEO | 2016/07/05
SECONDARY ACCESSION(S): PRJNA325005
REPOSITORIES: GEO
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