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Assay for Transposase-Accessible Chromatin with high throughput sequencing (ATAC-Seq) reveals lncRNA MANTIS important for the angiogenic function of endothelial cells

ABSTRACT: The angiogenic function of endothelial cells is tightly regulated but the impact of long non-coding RNAs (lncRNA) remains unclear. The lncRNA yielded to be an epigenetically restricted endothelial lncRNAs. Here, the chromatin accessibility after knockdown of MANTIS was investigated. It revealed changes on chromatin accessibility on several promoters which are known to be important for endothelial angiogenic function.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83427 | GEO | 2016/07/10

SECONDARY ACCESSION(S): PRJNA325880

REPOSITORIES: GEO

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