Transcriptomics

Dataset Information

0

Gene expression profiles of tumor epithelium and tumor-associated stroma of HER2+ breast tumors, plus normal epithelium and stroma from HER2+ and HER2- breast tumors


ABSTRACT: Breast cancer is a heterogeneous disease. This heterogeneity can be observed at multiple levels, including gene expression, chromosomal aberrations, and disease pathology. A clear understanding of these differences is important since they impact upon treatment efficacy and clinical outcome. Many studies have shown that the tumor microenvironment also plays a critical role in cancer initiation and progression. Although genomic technologies have been used to gain a better understanding of the impact of gene expression heterogeneity on breast cancer outcome by identifying gene expression signatures associated with clinical outcome, histopathological breast cancer subtypes, and a variety of cancer-related pathways and processes, relatively little is known about the spectrum of heterogeneity in the tumor microenvironment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE83591 | GEO | 2017/09/05

SECONDARY ACCESSION(S): PRJNA326438

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2019-02-22 | GSE88715 | GEO
2011-01-15 | GSE12622 | GEO
2008-04-11 | GSE9014 | GEO
2017-01-11 | PXD003632 | Pride
2008-06-16 | E-GEOD-9014 | biostudies-arrayexpress
2013-10-22 | E-GEOD-41656 | biostudies-arrayexpress
2019-02-22 | GSE88847 | GEO
2023-06-23 | PXD027012 | Pride
2013-10-22 | GSE41656 | GEO
2024-12-20 | GSE276527 | GEO