Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Male Rat DNA methylation in the Prefrontal Cortex at postnatal day 62 following prenatal restraint stress

ABSTRACT: DNA methylation profiling of Prefrontal Cortex of male rats at postnatal day 62 whose mothers were exposed to restraint stress from gestation day 14 until delivery

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE84021 | GEO | 2016/07/06

SECONDARY ACCESSION(S): PRJNA327828

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Male Rat DNA methylation in the Prefrontal Cortex at postnatal day 62 following prenatal restraint stress

Project description:DNA methylation profiling of Prefrontal Cortex of male rats at postnatal day 62 whose mothers were exposed to restraint stress from gestation day 14 until delivery The groups consist of 1. Control rats (Ctrl) 2. Prenatally stressed rats (PNS)

2016-07-06 | E-GEOD-84021 | biostudies-arrayexpress

Proteomic characterization of the medial prefrontal cortex in chronic restraint stress mice

Project description:In this study, we used chronic restraint stress to establish a mouse model of depression, and differentially expressed proteins in the medial prefrontal cortex of depressive model mice were detected by TMT proteomics. By functional enrichment analysis of the differentially expressed proteins, we found that CRS-induced mice have altered synaptic function and excessive autophagy. In addition, we also demonstrated that CRS may disrupt synaptic plasticity by affecting activation of the Wnt2b/尾-catenin pathway which may help explain the pathogenesis of depression and identify new antidepressant drug targets.

2024-08-27 | PXD054244 | Pride

Expression data from adult mouse Prefrontal Cortex following prenatal infection

Project description:Prenatal exposure to infectious or inflammatory insults can increase the risk of neuropsychiatric disorders with neurodevelopmental components, including schizophrenia and autism. The molecular processes underlying this pathological association are only partially understood. Here, we implemented an unbiased genome-wide transcriptional profiling of the prefrontal cortex of mice exposed to prenatal infection on GD17 compared to control subjects in order to elucidate the long term molecular signature of late prenatal infection. We used microarray analysis to investigate the long lasting gene expression changes in a well-established mouse model that is based on maternal treatment with the viral mimic poly(I:C) during pregnancy C57BL/6 mice were treated with the synthetic viral mimetic poly(I:C) (5 mg/kg, i.v.) or control (saline, i.v.) solution on gestation day 17. Offspring were subjected to cognitive and behavioral testing in adulthood, and then whole genome gene expression analysis with Affymetrix Microarray and subsequent q-PCR validation were performed on the prefrontal Cortex.

2016-03-01 | E-GEOD-77972 | biostudies-arrayexpress

Streptomyces sp. 62 strain:62

Project description:Streptomyces sp. 62 strain:62 Genome sequencing

| PRJNA402574 | ENA

A switch from neuronal network development to maintenance during postnatal development of rat prefrontal cortex

Project description:To unravel the gene expression changes during postnatal prefrontal cortex development, RNA-seq was performed in the rat medial prefrontal cortex at five time points from early life to adulthood (postnatal day 8, 14, 21, 35 and 70) and differential expression of protein-coding genes, lincRNAs and alternative exons was analyzed. A switch from neuronal network development to maintenance during postnatal rat prefrontal cortex development was shown.

2017-01-01 | GSE79860 | GEO

Rattus norvegicus

Project description:Male Rat DNA methylation in the Prefrontal Cortex at postnatal day 62 following prenatal restraint stress

| PRJNA327828 | ENA

Comparative phosphoproteomic profiling in prefrontal cortex of prenatal stressed offspring rats

Project description:We used MS-based TMT quantitative proteomics in combination with phosphopeptide enrichment method to compare phosphoproteomic profiling in prefrontal cortex of of PS-S and CON offspring rats.

2022-08-12 | PXD026563 | Pride

Acidovorax sp. 62 strain:62

Project description:Acidovorax sp. 62 strain:62 Genome sequencing and assembly

| PRJNA402408 | ENA

Transcription profiling of human prefrontal cortex during postnatal development

Project description:Fresh frozen post mortem prefrontal cortex tissue (Brodman area 46) was obtained from 44 individuals varying in age from 0 to 49 years. RNA was extracted from these samples and hybridized to HG133plus2.0 GeneChips. The data was used to examine patterns of gene expression over the course of human postnatal developmental and ageing. PMI - postmortem interval, DLPFC - dorsolateral prefrontal cortex Experiment Overall Design: The dataset consists of 44 individuals varying in age from 0 to 49 years

2009-12-02 | E-GEOD-13564 | biostudies-arrayexpress

Enterococcus faecalis 62 strain:62

Project description:Enterococcus faecalis 62 genome sequencing

| PRJNA61185 | ENA