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MRNA profiling in gastric cancer cell line AGS upon miR-25-3p silencing

ABSTRACT: Genome-wide mRNA expression profiling was performed in AGS, gastric cancer cell line, upon miR-25 silencing. At 48 hours upon anti-miR-25-3p (miRNA inhibitor) and non-targeting control RNA transfection, the whole transcriptome profiling was performed in triplicates. The miR-25 silencing elevates the diffuse gastric cancer features like expression of COL1A2, expression of COL1A2 co-expressed genes, Epithelial to Mesenchymal Transition (EMT) and angiogenesis associated genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84196 | GEO | 2016/12/07

SECONDARY ACCESSION(S): PRJNA328264

REPOSITORIES: GEO

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Homo sapiens

Project description:mRNA profiling in gastric cancer cell line AGS upon miR-25-3p silencing

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