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GE expression profile of PBMCs in healthy subjects and MS patients after extra virgin olive oil (EVOO) intake - PART 3 - MS Patients

ABSTRACT: Gene expression profiles of PBMCs in patients with MS following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of after EVOO intake. Results provide the information of changes in PBMCs transcriptome following EVOO intake.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84591 | GEO | 2016/07/19

SECONDARY ACCESSION(S): PRJNA330534

REPOSITORIES: GEO

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GE expression profile of PBMCs in healthy subjects and MS patients after extra virgin olive oil (EVOO) intake - PART 3 - MS Patients

Project description:Gene expression profiles of PBMCs in patients with MS following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of after EVOO intake. Results provide the information of changes in PBMCs transcriptome following EVOO intake. RNA obtained from PBMCs of the same patients before and after extra virgin olive oil intake (paired samples). Comparisons: T0 vs. T1 (paired samples)

2016-07-19 | E-GEOD-84591 | biostudies-arrayexpress

Gene expression profile of PBMCs in healthy subjects and MS Patients after extra virgin olive oil (EVOO) intake - Part 1 (Controls)

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Gene expression profile of PBMCs in healthy subjects and MS Patients after extra virgin olive oil (EVOO) intake - Part 1 (Controls)

Project description:Gene expression profiles of PBMCs in healthy subjects following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of after EVOO intake. Results provide the information of changes in PBMPs transcriptome following EVOO intake. RNA obtained from PBMCs of the same subjects before and after extra virgin olive oil intake (paired samples). Comparisons: T0 vs. T1 (paired samples) - Controls

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miRNA expression profile of PBMCs in healthy subjects after extra virgin olive oil (EVOO) intake - Part 2 (Controls)

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miRNA expression profile of PBMCs in healthy subjects after extra virgin olive oil (EVOO) intake - Part 2 (Controls)

Project description:miRNA expression profiles of PBMCs in healthy subjects following extra virgin olive oil intake. The aim of the present study was to investigate the whole-genome gene and miRNA profiles of PBMCs after EVOO intake. Results provide the information of changes in PBMPs transcriptome following EVOO intake. RNA obtained from PBMCs of the same patients before and after extra virgin olive oil intake (paired samples). Comparisons: T0 vs. T1 (paired samples) - Controls

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GE/miRNA expression profile of PBMCs in healthy subjects and MS patients after extra virgin olive oil (EVOO) intake

Project description:GE/miRNA expression profile of PBMCs in healthy subjects and MS patients after extra virgin olive oil (EVOO) intake

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Project description:Proteins and peptides are minor components of vegetal oils. The presence of these compounds in virgin olive oil was first reported in 2001, but the nature of the olive oil proteome is still a puzzling question for food science researchers. In this project, we have compiled for a first time a comprehensive proteomic dataset of olive fruit and fungal proteins that are present at low but measurable concentrations in a vegetable oil from a crop of great agronomical relevance as olive (Olea europaea L.). Accurate mass nLC-MS data were collected in high definition direct data analysis (HD-DDA) mode using the ion mobility separation step. Protein identification was performed using the Mascot Server v2.2.07 software (Matrix Science) against an ad hoc database made of olive protein entries. Starting from this proteomic record, the impact of these proteins on olive oil stability and quality could be tested. Moreover, the effect of olive oil proteins on human health and their potential use as functional food components could be also evaluated. In addition, this dataset provides a resource for use in further functional comparisons across other vegetable oils, and also expands the proteomic resources to non-model species, thus also allowing further comparative inter-species studies.

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GE/miRNA expression profile of PBMCs in healthy subjects and MS patients after extra virgin olive oil (EVOO) intake

Project description:This SuperSeries is composed of the SubSeries listed below.

2016-07-19 | GSE75027 | GEO