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MRNA expression profile of Tie2 monocytes in limb ischemia patients and controls

ABSTRACT: Tie2-expressing monocytes do not appear to effect revascularisation in critical limb ischemia (CLI) patients, despite a large body of evidence demonstrating their pro-angiogenic potential when isolated from control patients. In order to understand what might cause this loss of angiogenic function, we carried out a whole genome microarray analysis of mRNA isolated from Tie2-expressing monocytes from CLI patients and compared that with age-matched control samples.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84626 | GEO | 2016/07/21

SECONDARY ACCESSION(S): PRJNA330686

REPOSITORIES: GEO

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mRNA expression profile of Tie2 monocytes in limb ischemia patients and controls

Project description:Tie2-expressing monocytes do not appear to effect revascularisation in critical limb ischemia (CLI) patients, despite a large body of evidence demonstrating their pro-angiogenic potential when isolated from control patients. In order to understand what might cause this loss of angiogenic function, we carried out a whole genome microarray analysis of mRNA isolated from Tie2-expressing monocytes from CLI patients and compared that with age-matched control samples. 12 samples in total

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miRNA expression profiles of TIE2 expressing Monocytes (TEMs)

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Gene expression profiles of TIE2 expressing Monocytes (TEMs)

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Expression data: Venous malformation-causative TIE2-mutations mediate an AKT-dependent decrease in PDGFB

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Homo sapiens

Project description:miRNA expression profiles of TIE2 expressing Monocytes (TEMs)

| PRJNA282423 | ENA