Genomics

Dataset Information

0

Small RNA sequencing of large dense-core vesicle in bovine chromaffin cells


ABSTRACT: Objectives: MicroRNA (miRNA) can be released to the extracellular medium and participates in neuronal communication. We investigate the mechanisms of miRNA exocytosis by vesicle fusion as a neuromodulator in a manner that are disparate from silencing gene expression. Methods: Small RNA sequencing data of large dense-core vesicle were generated by next-generation sequencing (NGS) in triplicate using Illumina Hiseq 2500. Results: Large dense-core vesicles contain a variety of known and novel miRNAs inside including miR-375. Conclusion: miRNAs can be novel neuromodulators, which are stored in LDCVs and released by vesicle fusion by SNARE assembly and synaptotagmin-1

ORGANISM(S): Bos taurus

PROVIDER: GSE84834 | GEO | 2017/01/01

SECONDARY ACCESSION(S): PRJNA335347

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA331140 | ENA
2020-08-15 | MSV000085956 | MassIVE
2020-08-15 | MSV000085957 | MassIVE
2021-10-06 | MTBLS1503 | MetaboLights
2020-08-15 | MSV000085958 | MassIVE
2020-12-09 | PXD020859 | Pride
| PRJNA335347 | ENA
2019-06-24 | PXD013939 | Pride
2020-10-17 | GSE105090 | GEO
2021-03-11 | PXD021437 | Pride