Transcriptomics

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Expression data from the chronic myeloid leukemia cell line K562 with or without AF1q/MLLT11 overexpressing


ABSTRACT: AF1q/MLLT11 expression was significantly upregulated in CML patients and elevated AF1q expression was associated with disease progression. Enforced AF1q expression promoted cell survival, protected CML cells from IM treatment and increased engraftment of CML cells in vivo. We used microarrays in AF1q-overexpressing K562 cells and negative control cells to profile differentially expressed genes that might be involved in AF1q regulation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE84842 | GEO | 2017/12/01

SECONDARY ACCESSION(S): PRJNA335353

REPOSITORIES: GEO

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