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LncRNA Expression Signatures in Response to Jiangtang Tiaozhi Formular in T2DM with Obesity and Hyperlipidemia

ABSTRACT: In the study, patients with type 2 diabetes with obesity and hyperlipidemia were treated by traditional Chinese medicine Jiangtang Tiaozhi Prescription of 24 weeks, we chosed 6 effective cases, 6 invalid cases and 6 health people as control to analysis the molecular mechanism of TCM treatment. According to the research of LncRNA microarray, GO analysis, Pathway analysis, we found out the target LncRNAs, as well as their associated mRNAs were contribute to the good outcome of Jiangtang Tiaozhi Formula. Then we expand to 12 cases in each group for qPCR validation.

ORGANISM(S): Homo sapiens

PROVIDER: GSE85192 | GEO | 2017/08/31

SECONDARY ACCESSION(S): PRJNA336529

REPOSITORIES: GEO

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