Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data of human bone marrow mesenchymal cells (BM-MSC) from follicular patients (FL) or normal healthy donors (N)

ABSTRACT: GEP on Affymetrix U133+2.0 microarrays was performed on in vitro expanded bone marrow mesenchymal stroma cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE85229 | GEO | 2020/12/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression data of human follicular lymphoma (FL) B cells purifed from bone marrow samples (BM)

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on ex vivo cell-sorted FL B cells from infiltrated human BM samples, according to the CD20hiCD44loCD38posIgDnegCD138negCD34neg phenotype.

2022-06-01 | GSE152215 | GEO

Expression data from Bone-Marrow Mesenchymal Stromal Cells (BM-MSC) from Follicular Lymphoma patient (FL) or Healthy Donor (HD).

Project description:Human bone marrow mesenchymal stromal cells (BM-MSC) could be committed toward a functional lymphoid-like stroma by a combination of TNFalpha (TNF) and Lymphotoxin alpha1/beta2 (LT) (Amé-Thomas et al Blood 2007). Bone marrow and lymph node stromal cells support FL malignant cell recruitment and growth in particular after comittment to a lymphoid-like differentiation in vitro. In addition, more than 70% of FL patients exhibit a bone marrow involvment at diagnosis. We delineate using Affymetrix U133+2.0 microarrays the gene expression profile of BM-MSC obtained from FL patients (FL-MSC) and age-matched healthy donors (HD-MSC) in order to identify a specific FL-MSC signature. In addition, we used Affymetrix microarrays to define the gene expression signature of lymphoid-like stromal cells obtained from HD-MSC by treatment with TNF/LT in vitro. This TNF/LT signature was then used to interpret the gene expression profile of FL-MSC. GEP was performed on 10 BM-MSC from FL patients and 6 from healthy donors, treated or not with TNF(10 ng/mL)/LT(100ng/mL)

2012-01-26 | E-GEOD-35331 | biostudies-arrayexpress

Expression data from Bone-Marrow Mesenchymal Stromal Cells (BM-MSC) from Follicular Lymphoma patient (FL) or Healthy Donor (HD).

2012-01-26 | GSE35331 | GEO

Expression data of T follicular helper cells (Tfh) from follicular lymphoma lymph nodes (FL) or non malignant tonsils (TONS)

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on ex vivo cell-sorted Tfh from FL or TONS

2015-02-28 | GSE66384 | GEO

Expression data of human B lymphocytes from follicular lymphoma lymph nodes (FL)

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on ex vivo cell-sorted B lymphocytes from FL patients, according to the CD20hiCD44loCD38posIgDnegCD138neg phenotype.

2020-09-01 | GSE85233 | GEO

Expression data of human stromal cells isolated from Follicular lymphoma (FL) or non-malignant reactive (RLN) lymph nodes

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on in vitro expanded stromal cells

2021-05-25 | GSE152068 | GEO

Expression data of T follicular helper cells (Tfh) from follicular lymphoma lymph nodes (FL) or non malignant tonsils (TONS)

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on ex vivo cell-sorted Tfh from FL or TONS GEP was performed on 7 Tfh from FL and 7 Tfh from TONS

2015-02-28 | E-GEOD-66384 | biostudies-arrayexpress

Expression data of human CD19pos B lymphocytes (B) and CD19negCD22neg non-B cells (ENV) from non tumoral reactive lymph nodes (RLN), tonsils (TONS) or follicular lymphoma (FL)

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on ex vivo CD19+ B lymphocytes or CD19-CD22- fractions from reactive or FL lymph nodes or normal tonsils.

2019-05-27 | GSE107367 | GEO

Influence of follicular lymphoma B cells on tumor-supportive stromal cells gene expression

Project description:GEP on Affymetrix U133+2.0 microarrays was performed on in vitro expanded stromal cells with or without B cells priming.

2021-02-26 | GSE165007 | GEO

Expression of germinal center T follicular helper (GC-Tfh) cells and pre-Tfh cells from tonsils (Tons) and follicular lymphoma lymph nodes (FL).

Project description:GEP on Affymetrix Genechip HTA 2.0 microarrays was performed on ex vivo cell-sorted GC-Tfh and pre-Tfh from TONS and FL

2020-09-16 | GSE157801 | GEO