Genomics

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Reprogramming Mouse Fibroblasts into Engraftable Myeloerythroid and Lymphoid Progenitors: Induction and Underlying Mechanisms (ChIP-Seq)


ABSTRACT: Here we show that hematopoietic transcription factors Scl, Lmo2, Runx1 and Bmi1 can convert a developmentally-distant lineage (fibroblasts) into “induced hematopoietic progenitors” (iHPs). We analyzed transcriptomic data for cell undergoing the transdifferentiation process at several time-points of the process.

ORGANISM(S): Mus musculus

PROVIDER: GSE86197 | GEO | 2016/09/30

SECONDARY ACCESSION(S): PRJNA340870

REPOSITORIES: GEO

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