Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression profile of peri-implantation uteri treated with LPA3 receptor agonist

ABSTRACT: To investigate gene expression changes induced by Lysophosphatidic acid receptor 3 (LPA3) activation in peri-implantation uteri, we performed microarray analysis in LPA3 agonist (T13)-injected pseudopregnant uteri. On 3.5 dpc, pseudopregnant mice were subjected with intrautero-injection of vehicle (0.01% BSA-PBS) or T13 and then uteri were dissected 24-36 hr after the injection. We found that several thousand genes were up- or down-regulated by T13 injection. Interestingly, well-known decidual markers such as Bmp2 and Wnt4 were dramatically induced by T13, which we certificated in quantitive RT-PCR.

ORGANISM(S): Mus musculus

PROVIDER: GSE87161 | GEO | 2017/05/31

SECONDARY ACCESSION(S): PRJNA343767

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcription profile of K-ras activated murine menstruating uteri

2009-04-03 | GSE15518 | GEO

Transcription profile of K-ras activated murine menstruating uteri

Project description:The expression of K-ras transgene is induced in K-rasV12+/-/Cre+/+/ROSA26R-LacZ+/+ transgenic mice uteri, which were primed with hormone treatment. Decidualization was artificially induced in these uteri and hormone injection was withdrawn to induced menstruation-like endometrial degeneration. Microarray was then used to study the molecular changes in these menstruating uteri following the K-ras activation. Uterine tissues were collected from K-ras induced and littermate controled menstruating uteri. Experiments were carried out using Illumina Mouse WG-6 BeadChips (n=6 in each group). Data were normalized in R environment using the Lumi Bioconductor package.

2010-06-20 | E-GEOD-15518 | biostudies-arrayexpress

Mus musculus

Project description:Expression data of uteri treated with An Agonist for Lysophosphatidic acid receptor3 (LPA3), T13

| PRJNA343602 | ENA

Expression data of uteri treated with An Agonist for Lysophosphatidic acid receptor3 (LPA3), T13

Project description:Identification of the genes whose expression levels are regulated by T13 during peri-implantation period

2017-05-31 | GSE87116 | GEO

Mouse uteri at gestation day 13

Project description:Mouse uteri at gestation day 13

| PRJNA818348 | ENA

Expression profiling of the uteri of progesterone induced uterine gland knockout mice

Project description:To identify genes differentially expressed in the glandless uterus, whole uteri were collected from control (uterine glands present) and PUGKO (no uterine glands) mice at day of pseudopregnancy (DOPP) 3.5 (day DOPP 0.5= vaginal plug). Microarray analysis identified differentially expressed genes in the glandless uteri of PUGKO mice as compared to control mice.

2013-11-05 | GSE48340 | GEO

Murine uterus expression profile during Peri-implantation: Pre-implantation vs. Post-implantation

Project description:Anaylsis differentially expressed genes of mouse peri-implanted uteri comparing pre-implantation uteri (Day2, Day3 and Day4) with post-implantation uteri (Day6, Day7 and Day8) by microassay. This study has built a meaningful basis for future investigation in elucidating the molecular nature of maternal-fetal interactions during pregnancy establishment and maintenance. Pre-implantation uteri VS. Post-implantation uteri. Three biological replicates of each experiments: pre-implantation uteri (Day2, Day3 and Day4): 234, 234①, 234②; 3 mixture of post-implantation uteri (Day6, Day7 and Day8): 678, 678①, 678②. Two hybridizations were performed by using a reverse fluorescence strategy (Cy3, Cy5) for each sample.

2011-06-30 | E-GEOD-26615 | biostudies-arrayexpress

Murine uterus expression profile during Peri-implantation: Pre-implantation vs. Post-implantation

2011-06-30 | GSE26615 | GEO

LPS induced Cytokines & Chemokines changes in E9.5 pregnant mouse uteri

Project description:Changes of Cytokines and chemokines profiles were sucessfully determined between mouse non-treated vs LPS treated pregnant uteri using Qiagen PCR array.

2015-01-01 | GSE63246 | GEO

LPS induced Cytokines & Chemokines changes in E9.5 pregnant mouse uteri

Project description:Changes of Cytokines and chemokines profiles were sucessfully determined between mouse non-treated vs LPS treated pregnant uteri using Qiagen PCR array. Pregnant mouse (FVB strain E8.5-9.5) were treated with LPS(2.5ug/mouse) or saline as control. 8h- or 16-h later, uteri tissues (N=3) were collected.

2015-01-01 | E-GEOD-63246 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data