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RNA sequencing of LSK cells from mice with JAK2 mutation and HMGA2 expression

ABSTRACT: Either loss of EZH2 or redcuction of let-7 induces expression of HMGA2 and provokes severe myelofibrosis in mice carrying JAK2V617F. Therefore we compared gene expression profiles of LSK cells among WT mice, Hmga2-Tg mice, JAK2V617F-Tg mice, JAK2V617F/Hmga2 double-Tg mice, and JAK2V617F-Tg/EZH2 conditional KO mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE87464 | GEO | 2017/06/01

SECONDARY ACCESSION(S): PRJNA344851

REPOSITORIES: GEO

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