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Comparison of gene expression profilings between parental A549, OSK-A549-Colony and OSK-A549-SN

ABSTRACT: In the present study, we successfully generated lung cancer stem cell (CSC)-like cells by introducing a small set of transcription factors into a lung cancer cell line (OSK-A549-Colony). In addition to properties that are conventionally referred to as CSC properties, the lung induced CSCs exhibited the ability to form lung cancer-like tissues in vitro with vascular cells and mesenchymal stem cells, which showed structures and immunohistological patterns that were similar to human lung cancer tissues.

ORGANISM(S): Homo sapiens

PROVIDER: GSE89229 | GEO | 2017/11/09

SECONDARY ACCESSION(S): PRJNA350784

REPOSITORIES: GEO

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