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Effects of formin impairment on gene expression in Arabidopsis seedlings

ABSTRACT: Formins (FH2 proteins) are a family of evolutionarily conserved proteins involved in many aspects of cytoskeletal organization and signalling, shown in some cases to participate in transcriptional regulation in metazoans. However, nothing is known about their possible involvement in the regulation of gene expression in angiosperms. We examined the effects of mutational loss of the main housekeeping Arabidopsis thaliana formin, FH1 ((At3g25500) on global gene expression pattern in 7 days old seedlings and compared them with the effect of treatment with SMIFH2, a broad-spectrum inhibitor of formin function.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE89466 | GEO | 2018/01/24

REPOSITORIES: GEO

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