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MicroRNA expression profiling in a mouse spinal cord injury model [P15 and P90, 12h and 3d]

ABSTRACT: Spinal cord injury (SCI) is a devastating condition resulting in permanent and irreversible deficits. Despite regeneration attempts, the neurons fail due to several dysfunctions. A number of studies have already revealed that, following SCI, microRNAs show two opposite kinds of alterations, one detrimental and one protective. However, there is still little evidence of specific microRNAs involved in axon regrowth. The aim of this project is the characterization of microRNA expression changes in sensorimotor cortex and corticospinal motor neurons, whose axons are severed by SCI.

ORGANISM(S): Mus musculus

PROVIDER: GSE89517 | GEO | 2021/04/21

REPOSITORIES: GEO

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MicroRNA expression profiling in a mouse spinal cord injury model [P90, 7d]

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