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Transcriptome assembly and candidate genes involved in nutritional programming in Xiphophorus multilineatus

ABSTRACT: Nutritional programming takes place in early development. Variation in the quality and/or quantity of nutrients in early development can influence long-term health and viability. However, little is known about the mechanism of nutritional programming. The live-bearing fish Xiphophorus multilineatus, has the potential to be a new model for understanding these mechanisms, given evidence of both genetic and nutritional programming influences on juvenile growth rate. To study the molecular signatures of nutritional programming, we assembled a de novo transcriptome for X. multilineatus, and used RNA-Seq to profile gene expression in the brains of males reared in low and high quality juvenile environments. We found131 genes were differentially expressed, including metabolism and appetite master regulator agrp gene.

ORGANISM(S): Xiphophorus multilineatus

PROVIDER: GSE89561 | GEO | 2017/01/15

SECONDARY ACCESSION(S): PRJNA352550

REPOSITORIES: GEO

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