Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids Ib

ABSTRACT: We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Keywords: regulation of gene expression

ORGANISM(S): Cricetulus griseus Mus musculus

PROVIDER: GSE9041 | GEO | 2008/03/13

SECONDARY ACCESSION(S): PRJNA105313

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids Ia

2008-03-13 | GSE9033 | GEO

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids (control II)

2008-03-13 | GSE9068 | GEO

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids (control I)

2008-03-13 | GSE9040 | GEO

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids II

Project description:We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Proof of principle transfection experiment. Pcdh7 (a gene identified as being a regulator of many genes) is transfected into A23 and HEK cells and compared to A23 and HEK cells transfected with an empty vector. Upregulated genes predicted by our approach are compared with the transfection experiments Keywords: tranfection, regulation of gene expression

2008-03-13 | GSE9066 | GEO

Transcription profiling of mouse and hamster radiation hybrids to map regulatory loci for protein coding genes

Project description:We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Experiment Overall Design: 99 RH cells with biological replicates (198 total) and biological replicates of mouse brain RNA vs. hamster brain RNA and mouse liver RNA vs. hamster liver RNA (4 total)

2008-04-04 | E-GEOD-9033 | biostudies-arrayexpress

Mapping regulatory loci protein coding genes IN THE mouse genome USING microarray measurements FROM a panel OF mouse/hamster radiation hybrids (control I)

Project description:We have mapped regulatory loci for nearly all protein coding genes in the mammalian genome using microarray measurements from a panel of mouse/hamster radiation hybrids. Experiment Overall Design: Five replicas of RNA from the A23 cell line vs. itself. These arrays serve as a control to determine the power to detect cis ceQTLs in this experiment.

2008-04-04 | E-GEOD-9040 | biostudies-arrayexpress

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids Ib

Project description:Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids Ib

| PRJNA105313 | ENA

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids Ia

Project description:Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids Ia

| PRJNA105309 | ENA

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids II

Project description:Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids II

| PRJNA105325 | ENA

Fine mapping of regulatory loci for mammalian gene expression using radiation hybrids.

Project description:We mapped regulatory loci for nearly all protein-coding genes in mammals using comparative genomic hybridization and expression array measurements from a panel of mouse-hamster radiation hybrid cell lines. The large number of breaks in the mouse chromosomes and the dense genotyping of the panel allowed extremely sharp mapping of loci. As the regulatory loci result from extra gene dosage, we call them copy number expression quantitative trait loci, or ceQTLs. The -2log10P support interval for the ceQTLs was <150 kb, containing an average of <2-3 genes. We identified 29,769 trans ceQTLs with -log10P > 4, including 13 hotspots each regulating >100 genes in trans. Further, this work identifies 2,761 trans ceQTLs harboring no known genes, and provides evidence for a mode of gene expression autoregulation specific to the X chromosome.

| S-EPMC3014048 | biostudies-literature

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data