Genomics

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PIWI-associated piRNA in Drosophila melanogaster ovary


ABSTRACT: Heterochromatin, representing the silenced state of transcription, largely consists of transposon-enriched and highly repetitive sequences. Implicated in heterochromatin formation and transcriptional silencing in Drosophila are PIWI and repeat-associated small interfering RNAs (rasiRNAs). Despite this, the role of PIWI in rasiRNA expression and heterochromatic silencing remains unknown. Here we report the identification and characterization of 12,903 PIWI-interacting RNAs (piRNAs) in Drosophila, demonstrating that rasiRNAs represent a subset of piRNAs. Keywords: PIWI, piRNA, epigenetic regulation, heterochromatin

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE9138 | GEO | 2007/10/25

SECONDARY ACCESSION(S): PRJNA102681

REPOSITORIES: GEO

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