Transcriptomics

Dataset Information

0

The polycomb protein MEL-18/PCGF2 regulates ErbB phosphorylation in HER2-positive breast cancer


ABSTRACT: Gene expression analysis on MEL-18-knockdown BT474 cells. MEL-18, a polycomb group protein and a member of the polycomb repressive complex 1 (PRC1), have suggested as a tumor suppressor in several cancer, including breast cancer. The results provides that the depletion of MEL-18 in HER2-positive breast cancer causes the activation of ErbB signaling pathway. We proposed that MEL-18 is a novel prognostic and therapeutic marker for HER2-positive breast cancer.

ORGANISM(S): Homo sapiens

PROVIDER: GSE92504 | GEO | 2018/07/31

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

2022-03-01 | GSE115591 | GEO
2022-03-01 | GSE115586 | GEO
2015-05-01 | GSE64716 | GEO
2015-05-01 | E-GEOD-64716 | biostudies-arrayexpress
| PRJNA357727 | ENA
2007-05-01 | GSE7578 | GEO
2013-10-31 | GSE51889 | GEO
2021-07-05 | GSE179280 | GEO
2013-10-31 | E-GEOD-51889 | biostudies-arrayexpress
2007-10-31 | E-GEOD-7578 | biostudies-arrayexpress